Analogous to mixed tumors of salivary glands ( pleomorphic adenomas ), cutaneous mixed tumors ( chondroid syringomas ) contain a ductal (epithelial) component and a variably prominent myoepithelial component tumors showing purely myoepithelial differentiation (myoepitheliomas) have only recently been recognized to arise in the dermis, and to date very few cases have been described. Myoepithelial carcinoma is a rare malignant (cancerous) tumor that usually occurs in the salivary glands in the mouth, but can also occur in skin and soft tissues approximately 66% of these tumors occur in a part of the salivary gland, known as the parotid gland. ↑nagao, t sugano, i ishida, y tajima, y matsuzaki, o konno, a kondo, y nagao, k (oct 1998) salivary gland malignant myoepithelioma: a. Well circumscribed dermal lesions, not connected to epidermis, may extend into superficial subcutis either composed of: solid proliferation of ovoid, spindled, histiocytoid or epithelioid cells with abundant eosinophilic syncytial cytoplasm and little stroma or. The authors address a group of loosely associated, characteristically benign soft tissue neoplasms that exhibit partial myoid differentiation the entities share similarities in morphology and in nomenclature that have historically created confusion the authors attempt to clarify the distinct architectural patterns and the corresponding immunophenotypic and ultrastructural features that.
Cutaneous syncytial myoepithelioma is a recently described rare tumor of the dermis it is derived and composed purely of myoepithelial cells and shows a characteristic syncytial growth pattern of. Myoepithelial tumors cutaneous syncytial myoepithelioma ema s-100 protein background & objective: myoepithelial tumors arising in the dermis, subcutaneous fat or soft tissue are exceedingly rare commonly, cutaneous myoepitheliomas behave in a benign fashion, however, local recurrence and metastasis have been documented. Myoepithelioma is a rare benign neoplasm of salivary gland derivation, definited as composed of myoepithelial cells and first described in 1943 1 myoepithelial cells exhibite a dual epithelial and smooth muscle phenotype, have contractile properties and are present in many secretory organs.
To characterize these tumors further, 14 cutaneous myoepithelial tumors were retrieved from the authors’ consult files cutaneous myoepithelioma: a clinicopathologic and immunohistochemical study of 14 cases - human pathology. Excretion: eccrine sweat gland secretion can also provide a significant excretory route for water and electrolytes  protection: eccrine sweat gland secretion aids in preserving the skin's acid mantle , which helps protect the skin from colonization from bacteria and other pathogenic organisms. In summary, cutaneous syncytial myoepithelioma is a morphologically distinct variant that more frequently affects men, occurs over a wide age range, and usually presents on the extremities tumors are positive for s-100 protein and ema, and, unlike most myoepithelial neoplasms, keratin staining is infrequent. Cutaneous myoepithelioma is a very rare, benign, subcutaneous and dermal tumor it usually presents as a slow-growing and painless mass on the extremities we report a case of cutaneous myoepithelioma that was located on the foot.
Cutaneous myoepithelial tumors demonstrate heterogenous morphologic and immunophenotypic features we previously described, in brief, 7 cases of cutaneous myoepithelioma showing solid syncytial growth of ovoid, spindled, or histiocytoid cells we now present the clinicopathologic features in a series of 38 cases of this distinctive syncytial variant, which were diagnosed between 1997 and 2012. According to this description, myoepithelioma and mixed tumors arising in the skin and subcutis represent points along a clinicopathologic spectrum of cutaneous and soft-tissue tumors to the best of our knowledge, there has been only one case report of an entirely cutaneous myoepithelioma in the literature. Home / ogh reports, vol 5, issue 2, jul-dec 2015 / cutaneous myoepithelioma: a case report of an unusual and recently recognized entity cutaneous myoepithelioma: a case report of an unusual and recently recognized entity.
Myoepithelioma of the head and neck, also myoepithelioma, is a salivary gland tumour of the head and neck that is usually benign as the name suggests, it consists of myoepithelial cells classically, they are found in the parotid gland or palate. Cutaneous syncytial myoepithelioma is a morphologically distinct subtype of myoepithelial neoplasm that is characterized by solid growth of spindled, ovoid, or histiocytoid cells with palely eosinophilic cytoplasm and a distinct immunophenotype of ema and s-100 positivity and infrequent cytokeratin staining. Myoepithelioma (me) is defined as a tumour composed of myoepithelial cells that exhibit spindle, epithelioid, plasmacytoid or clear cytoplasmic features the tumour is composed of myoepithelial cells.
Cutaneous myoepithelioma with cartilaginous metaplasia: a new (but not surprising) histopathologic feature ashley r mason md†, shelby y kunishima md†, jonathan d cuda md , jennifer m mcniff md . Cutaneous myoepithelioma skin myoepithelioma eck myoepithelioma myoepithelioma on the skin case report cutaneous myoepithelioma (cm) is a rare, benign, subcutaneous or dermal tumor  the tumor typically presents on the extremities as a small, slow-growing subepidermal mass. Background: cutaneous myoepithelioma, both benign and malignant, is a rare neoplasm composed of neoplastic myoepithelial cells showing diverse histopathological features, and criteria for. The term “myoepithelioma” of the skin and subcutis to refer to a neoplasm with predominantly myoepithelial differentiation however, cutaneous myoepithelial neoplasms are extremely rare only 44 cases have been reported to date6-11 the reported cases.